About 3 results found for searched term "LLY-283" (0.191 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M6312 | LLY-283 | PRMTs |
| LLY-283 is the potent and selective SAM-competitive chemical probe for PRMT5. It inhibits PRMT5 enzyme activity with IC50 of 20 nM for methylation of an H4R3 derived peptide substrate, and shows greater than 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. | ||
| M20623 | LLY-284 | Histone Methyltransferase |
| LLY-284 is the diastereomer of LLY-283, which is a potent and selective SAM-competitive chemical probe for PRMT5. LLY-284 is much less active than LLY-283 and can be used as a negative control for LLY-283. | ||
| M30157 | β-Glucuronidase-IN-1 | Antibiotic |
| β-Glucuronidase-IN-1 is a potent, selective, uncompetitive, and orally active E. coli bacterial β-glucuronidase inhibitor, exhibiting an IC50 and a Ki of 283 nM and 164 nM, respectively. | ||
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