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Tirzepatide hydrochloride

Cat. No. M9487
Tirzepatide hydrochloride Structure
Synonym:

LY3298176 hydrochloride

Size Price Availability Quantity
5mg USD 990  USD1100 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Tirzepatide hydrochloride (LY3298176 hydrochloride) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 4849.91
Formula C225H348N48O68.HCl
CAS Number
Purity >98%
Solubility
Storage at -20°C
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Tirzepatide hydrochloride, LY3298176 hydrochloride supplier, Glucagon Receptor, inhibitors

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