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Taltirelin acetate (TA-0910 acetate) is an oral active TRH analogue. Taltirelin acetate (TA-0910 acetate) is a superagonist at thyrotropin-releasing hormone receptor (TRH-R) with an IC50 of 910 nM. The EC50 value for stimulating an increase in cell solute Ca2+ concentration (Ca2+ release) was 36 nM.
| Molecular Weight | 465.46 |
| Formula | C19H27N7O7 |
| CAS Number | 1549593-23-8 |
| Solubility (25°C) | DMSO 100 mg/mL |
| Storage | -20°C, dry, sealed |
| Related Thyroid Hormone Receptor Products |
|---|
| Thyroid hormone receptor antagonist (1-850)
Thyroid hormone receptor antagonist (1-850) is a competitive, selective and high-affinity thyroid hormone receptor (TR) antagonist with an IC50 of 1.5 μM for antagonizing the effect of T3 on TR. Thyroid hormone receptor antagonist (1-850) blocks T3-mediated interaction of TRα and TRβ with nuclear receptor coactivator. |
| CO23
CO23 is a selective thyroid hormone receptor (TR) α agonist, it is used for growth and development regulation. CO23 can be transported through the blood-brain barrier. |
| 3,5-Diiodothyropropionic acid
3,5-Diiodothyropropionic acid is a thyroid hormone analog, induces α-myosin heavy chain mRNA expression, binds to thyroid hormone receptor (TR), with Ka of 2.40 and 4.06 M-1 for TRα1 and TRβ1, respectively. |
| ZYT-1
ZYT-1 is a thyroid receptor (THR-β) agonist. |
| VK-0214
VK-0214 is an orally active, selective small molecule agonist of the thyroid receptor (THR-β) for studies related to X-linked adrenoleukodystrophy (X-ALD) and hyperlipidemia. |
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