Free shipping on all orders over $ 500

Plumieride

Cat. No. M16880
Plumieride Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Plumieride

Chemical Information
CAS Number 511-89-7
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Ana Paula Dalmagro, et al. Nat Prod Res. Plumieride exerts anxiolytic-like effect mediated by GABAergic and monoaminergic systems

[2] Thaise Boeing, et al. Biomed Pharmacother. Antioxidant and anti-inflammatory effect of plumieride in dextran sulfate sodium-induced colitis in mice

[3] Tiago J Bonomini, et al. Regul Toxicol Pharmacol. Neuropharmacological and acute toxicological evaluation of ethanolic extract of Allamanda cathartica L. flowers and plumieride

[4] Jasvinder Singh, et al. Int Immunopharmacol. Immunostimulatory activity of plumieride an iridoid in augmenting immune system by targeting Th-1 pathway in balb/c mice

[5] T N Tiwari, et al. Phytother Res. Plumieride from Allamanda cathartica as an antidermatophytic agent

Related Iridoids Products
Jasminin

Jasminin

Oleoside

Oleoside

Cerbinal

Cerbinal

Rupesin E

Rupesin E

Jasmoside

Jasmoside

  Catalog
Abmole Inhibitor Catalog




Keywords: Plumieride supplier, Iridoids, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.