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Pigment Yellow 14

Cat. No. M42857
Pigment Yellow 14 Structure
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Quality Control & Documentation
Biological Activity

Pigment Yellow 14 is a fluorescent dye.

Chemical Information
Molecular Weight 657.55
Formula C34H30Cl2N6O4
CAS Number 5468-75-7
Form Solid
Storage -20°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Yu Wei et al. Anim Biosci. Effects of different types of xanthophyll extracted from marigold on pigmentation of yellow-feathered chickens

[2] Ashish Kothari et al. Eur J Med Res. Association of multidrug resistance behavior of clinical Pseudomonas aeruginosa to pigment coloration

[3] Sun Wook Jeong et al. Mar Drugs. Isolation and Characterization of a Yellow Xanthophyll Pigment-Producing Marine Bacterium, Erythrobacter sp. SDW2 Strain, in Coastal Seawater

[4] Akira Obana et al. PLoS One. Macular pigment changes after cataract surgery with yellow-tinted intraocular lens implantation

[5] M La Placa et al. J Eur Acad Dermatol Venereol. Lycopenaemia

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