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Ozagrel sodium

Cat. No. M5847
Ozagrel sodium Structure
Synonym:

OKY-046 sodium

Size Price Availability Quantity
10mg USD 75  USD75 In stock
50mg USD 200  USD200 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

Ozagrel(OKY-046) sodium salt is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 250.23
Formula C13H11N2NaO2
CAS Number 130952-46-4
Purity >98%
Solubility 44 mg/mL in water
Storage at -20°C
References

[1] Park SI, et al. Brain Res. Preischemic neuroprotective effect of minocycline and sodium ozagrel on transient cerebral ischemic rat model.

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