Free shipping on all orders over $ 500

Ozagrel sodium

Cat. No. M5847
Ozagrel sodium Structure
Synonym:

OKY-046 sodium

Size Price Availability Quantity
10mg USD 75  USD75 In stock
50mg USD 200  USD200 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Ozagrel(OKY-046) sodium salt is an antiplatelet agent working as a thromboxane A2 synthesis inhibitor.

Chemical Information
Molecular Weight 250.23
Formula C13H11N2NaO2
CAS Number 130952-46-4
Solubility (25°C) 44 mg/mL in water
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Park SI, et al. Brain Res. Preischemic neuroprotective effect of minocycline and sodium ozagrel on transient cerebral ischemic rat model.

Related Factor Xa Products
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride

Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate.

D-Pro-Phe-Arg-Chloromethylketone

D-Pro-Phe-Arg-Chloromethylketone, a inhibitor of coagulation factor XII and plasma kallikrein, plays an important role in thrombosis and inflammation.

Methoxycarbonyl-D-Nle-Gly-Arg-pNA

Methoxycarbonyl-D-Nle-Gly-Arg-pNA is a synthetic trypsin that can serve as a substrate for coagulation factors IXa (FIXa) and Xa (FXa).

Boc-Ile-Glu-Gly-Arg-AMC

Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination.

Delparantag

Delparantag (PMX-60056) is a salicylamide derivative and an effective unfractionated heparin (UFH) and low molecular weight heparin (LMWH) reversing agent.

  Catalog
Abmole Inhibitor Catalog




Keywords: Ozagrel sodium, OKY-046 sodium supplier, Factor Xa, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.