NBD-F is a fluorescent derivatization reagent for amino acid analysis.
Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
Animal A Km |
For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.
Molecular Weight | 183.1 |
Formula | C6H2FN3O3 |
CAS Number | 29270-56-2 |
Purity | >99% |
Solubility | DMSO ≥ 60 mg/mL |
Storage | 2-8°C, dry, protect from light, sealed |
Development of an LC-MS/MS method for the analysis of free sphingoid bases using 4-fluoro-7-nitrobenzofurazan (NBD-F).
Ishikawa T, et al. Lipids. 2014 Mar;49(3):295-304. PMID: 24310230.
Determination of amino acid neurotransmitters in rat hippocampi by HPLC-UV using NBD-F as a derivative.
Wu X, et al. Biomed Chromatogr. 2014 Apr;28(4):459-62. PMID: 24132719.
Related Fluorescent Dye Products |
---|
Fluo 3-AM |
Streptavidin-FITC
Streptavidin is a tetrameric protein purified from Streptomyces sp. that binds very tightly to the vitamin biotin with a Kd of ~ 10-14 mol/l. |
Coumarin 6
Coumarin 6 is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro. |
Calcein
Calcein is a fluorescent dye and self-quenching probe, used as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium. |
4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene
4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene (BODIPY 493/503) is a lipophilic fluorescent probe that localizes to polar lipids and can be used to label cellular neutral lipid contents, particularly those localized to lipid droplets, in live and fixed cells. |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.