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N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine)

Cat. No. M10428
N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine) Structure
Synonym:

D-GalNAc

Size Price Availability Quantity
100mg USD 45  USD50 In stock
500mg USD 90  USD100 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine) is an endogenous metabolite, it is the important constituent of brain heteropolysaccharides (glycoproteins).

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 221.21
Formula C8H15NO6
CAS Number 1811-31-0
Purity >98%
Solubility Water 90 mg/mL
DMSO 70 mg/mL
Storage at -20°C
References

Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization
K D Mazany, et al. Biochim Biophys Acta. 1998 Jul 1;1407(1):92-7. PMID: 9639683.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine), D-GalNAc supplier, Endogenous Metabolite, inhibitors

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