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N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine) is an endogenous metabolite, it is the important constituent of brain heteropolysaccharides (glycoproteins).
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Molecular Weight | 221.21 |
| Formula | C8H15NO6 |
| CAS Number | 1811-31-0 |
| Purity | >98% |
| Solubility | Water 90 mg/mL DMSO 70 mg/mL |
| Storage | at -20°C |
Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization
K D Mazany, et al. Biochim Biophys Acta. 1998 Jul 1;1407(1):92-7. PMID: 9639683.
| Related Endogenous Metabolite Products |
|---|
| Phosphocreatine disodium
Phosphocreatine disodium is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction, belongs to alpha amino acids and derivatives. |
| O-Acetyl-L-carnitine hydrochloride
O-Acetyl-L-carnitine hydrochloride is an acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS. |
| Myristic acid
Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils. |
| Atranorin
Atranorin is a lichen secondary metabolite which shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical. |
| Glutamic acid (L-Glutamic acid)
L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). |
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