N-Acetyl-D-galactosamine (D-N-Acetylgalactosamine) is an endogenous metabolite, it is the important constituent of brain heteropolysaccharides (glycoproteins).
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Solubility||Water 90 mg/mL
DMSO 70 mg/mL
Human chondroitin 6-sulfotransferase: cloning, gene structure, and chromosomal localization
K D Mazany, et al. Biochim Biophys Acta. 1998 Jul 1;1407(1):92-7. PMID: 9639683.
|Related Endogenous Metabolite Products|
Phosphocreatine disodium is a substrate for the determination of creatine kinase and used to regenerate ATP during skeletal muscle contraction, belongs to alpha amino acids and derivatives.
O-Acetyl-L-carnitine hydrochloride is an acetic acid ester of CARNITINE that facilitates movement of ACETYL COA into the matrices of mammalian MITOCHONDRIA during the oxidation of FATTY ACIDS.
Myristic acid is a saturated 14-carbon fatty acid occurring in most animal and vegetable fats, particularly butterfat and coconut, palm, and nutmeg oils.
Atranorin is a lichen secondary metabolite which shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical.
|Glutamic acid (L-Glutamic acid)
L-Glutamic acid acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA).
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