Free shipping on all orders over $ 500

Methyllinderone

Cat. No. M16233
Methyllinderone Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Methyllinderone

Chemical Information
CAS Number 3984-73-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Jae-Hwan Yoon, et al. J Microbiol Biotechnol. Methyl Linderone Suppresses TPA-Stimulated IL-8 and MMP-9 Expression Via the ERK/STAT3 Pathway in MCF-7 Breast Cancer Cells

[2] Xiangmin Song, et al. Molecules. Natural Product-Based Pesticide Discovery: Design, Synthesis and Bioactivity Studies of N-Amino-Maleimide Derivatives

[3] Eui Il Hwang, et al. Planta Med. Inhibition of chitin synthase 2 and antifungal activity of lignans from the stem bark of Lindera erythrocarpa

[4] Hyun-Mi Oh, et al. Bioorg Med Chem. Cyclopentenediones, inhibitors of farnesyl protein transferase and anti-tumor compounds, isolated from the fruit of Lindera erythrocarpa Makino

[5] Y Aoyama, et al. Bioorg Med Chem Lett. Total synthesis of human chymase inhibitor methyllinderone and structure--activity relationships of its derivatives

Related Chalcones Products
Lucidone

Lucidone

Asebotin

Asebotin

Kuraridin

Kuraridin

Maesopsin

Maesopsin

Pashanone

Pashanone

  Catalog
Abmole Inhibitor Catalog




Keywords: Methyllinderone supplier, Chalcones, inhibitors, activators


Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.