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Methoxy-X04

Cat. No. M6952

All AbMole products are for research use only, cannot be used for human consumption.

Methoxy-X04 Structure
Size Price Availability Quantity
5mg USD 90  USD90 In stock
10mg USD 155  USD155 In stock
25mg USD 300  USD300 In stock
50mg USD 540  USD540 In stock
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Quality Control & Documentation
Biological Activity

Methoxy-X04 is a fluorescent amyloid β (Aβ) probe for the detection and quantification of plaques, tangles and cerebrovascular amyloid. Displays high in vitro binding affinity (Ki = 26.8 nM); binds selectively to fibrillar β-sheet deposits. Brain penetrant.

Product Citations
Chemical Information
Molecular Weight 344.4
Formula C23H20O3
CAS Number 863918-78-9
Solubility (25°C) DMSO 34.44 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Fei Liang, et al. Neuroscience. Treadmill Exercise Promotes Microglial β-Amyloid Clearance and Prevents Cognitive Decline in APP/PS1 Mice

[2] Christian Rupprecht, et al. Pharmacopsychiatry. Morphological Representation of C1q in the Aging Central Nervous System

[3] Georgia-Ioanna Kartalou, et al. J Neurosci Methods . Golgi-Cox impregnation combined with fluorescence staining of amyloid plaques reveals local spine loss in an Alzheimer mouse model

[4] Matthias Brendel, et al. J Nucl Med. Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study

[5] Sams, et al. J Med Chem. Discovery of phosphoric acid mono-{2-[(E/Z)-4-(3,3-dimethyl-butyrylamino)-3,5-difluoro-benzoylimino]-thiazol-3-ylmethyl} ester (Lu AA47070): a phosphonooxymethylene prodrug of a potent and selective hA2A receptor antagonist.

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Keywords: Methoxy-X04 supplier, Amyloid, inhibitors, activators

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Products are for research use only. Not for human use. We do not sell to patients.
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