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Luvangetin

Cat. No. M16319
Luvangetin Structure
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Biological Activity

Luvangetin

Chemical Information
CAS Number 483-92-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Andrey S Erst, et al. Int J Mol Sci. Investigation of Chemical Constituents of Eranthis longistipitata (Ranunculaceae): Coumarins and Furochromones

[2] Yongtong Xiong, et al. Molecules. Screening Effective Antifungal Substances from the Bark and Leaves of Zanthoxylum avicennae by the Bioactivity-Guided Isolation Method

[3] Hoang Le Tuan Anh, et al. Pharm Biol. Anti-inflammatory coumarins from Paramignya trimera

[4] F A Macas, et al. J Chem Ecol. Allelochemicals fromPilocarpus goudotianus leaves

[5] Xue-Li Cao, et al. J Chromatogr B Analyt Technol Biomed Life Sci. Isolation of anti-tumor compounds from the stem bark of Zanthoxylum ailanthoides Sieb. & Zucc. by silica gel column and counter-current chromatography

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