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Kinsenoside

Cat. No. M9604
Kinsenoside Structure
Size Price Availability Quantity
5mg USD 240 In stock
10mg USD 400 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >97%
  • COA
  • MSDS
Biological Activity

Kinsenoside is a main active component isolated from plants of the genus Anoectochilus, and exhibits many biological activities and pharmacological effects. Kinsenoside rescues the nucleus pulposus cells (NPCs) viability under oxidative stress and protects against apoptosis, senescence and mitochondrial dysfunction in a Nrf2-dependent way.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 264.23
Formula C10H16O8
CAS Number 151870-74-5
Purity >97%
Solubility DMSO
Storage 2-8°C, dry, protect from light, sealed
References

Kinsenoside Ameliorates Intervertebral Disc Degeneration Through the Activation of AKT-ERK1/2-Nrf2 Signaling Pathway
Yanqiu Wang, et al. Aging (Albany NY). 2019 Sep 23;11(18):7961-7977. PMID: 31546235.

Kinsenoside: A Promising Bioactive Compound From Anoectochilus Species
Chang-Xing Qi, et al. Curr Med Sci. 2018 Feb;38(1):11-18. PMID: 30074146.

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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: Kinsenoside supplier, Nrf2, inhibitors

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