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Jasminoside

Cat. No. M16878
Jasminoside Structure
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Biological Activity

Jasminoside

Chemical Information
CAS Number 82451-18-1
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Kandasamy Saravanakumar, et al. Pharmaceuticals (Basel). Metabolite Profiling of Methanolic Extract of Gardenia jaminoides by LC-MS/MS and GC-MS and Its Anti-Diabetic, and Anti-Oxidant Activities

[2] Yang-Jing Luo, et al. Zhong Yao Cai. [Study on chemical constituents of Gardenia jasminoides(III)]

[3] Kaifeng Peng, et al. Bioorg Med Chem Lett. Chemical constituents from the fruit of Gardenia jasminoides and their inhibitory effects on nitric oxide production

[4] Mizuho Ohno, et al. J Nat Med. New spirostanol glycosides from Solanum nigrum and S. jasminoides

[5] Quan Cheng Chen, et al. J Nat Prod. Pyronane monoterpenoids from the fruit of Gardenia jasminoides

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