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Hyperforin is a transient receptor typical 6 (TRPC6) channel activator that regulates Ca2+ levels by activating Ca2+-transducing non-selective typical TRPC6 channels, with antidepressant and antitumor activities. In addition, Hyperforin modulates IL-17α secretion from γδ T cells and ameliorates Imiquimod-induced skin inflammation in psoriasis-like mice.
| Molecular Weight | 536.78 |
| Formula | C35H52O4 |
| CAS Number | 11079-53-1 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Mariam Gaid, et al. Biotechnological production of hyperforin for pharmaceutical formulation
[3] Kristina Friedland, et al. Hyperforin: To Be or Not to Be an Activator of TRPC(6)
[4] C Billard, et al. Mechanistic insights into the antileukemic activity of hyperforin
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