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Fura-2 AM

Cat. No. M9807
Fura-2 AM Structure
Size Price Availability
1mg USD 387 4-7 Days
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Quality Control
  • Current batch:
  • Purity >99%
  • COA
  • MSDS
Biological Activity

Fura-2 AM is a ratiometric fluorescent Ca2+ indicator.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 1001.85
Formula C44H47N3O24
CAS Number 108964-32-5
Purity >99%
Solubility DMSO
Storage -20°C, protect from light, dry, sealed
References

Calcium imaging of cortical neurons using Fura-2 AM
Odmara L Barreto-Chang, et al. J Vis Exp. 2009 Jan 19;(23):1067. PMID: 19229178.

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  Catalog
Abmole Inhibitor Catalog 2017




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