Free shipping on all orders over $ 500

FITC-Dextran

Cat. No. M9390
FITC-Dextran Structure
Size Price Availability Quantity
10mg USD 85 In stock
50mg USD 250 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity MW. ~10000
  • COA
  • MSDS
Biological Activity

FITC-Dextran is a marker consisting of coupling fluorescein-isothiocyanate to dextran.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight
Formula
CAS Number 60842-46-8
Purity MW. ~10000
Solubility Water ≥ 30 mg/mL
Storage 4°C, protect from light, dry, sealed
References

Analysis of Lysosomal pH by Flow Cytometry Using FITC-Dextran Loaded Cells.
Eriksson I, et al. Methods Mol Biol. 2017;1594:179-189. PMID: 28456983.

Fluorescein Isothiocyanate (FITC)-Dextran Extravasation as a Measure of Blood-Brain Barrier Permeability.
Natarajan R, et al. Curr Protoc Neurosci. 2017 Apr 10;79:9.58.1-9.58.15. PMID: 28398646.

High and Low Molecular Weight Fluorescein Isothiocyanate (FITC)-Dextrans to Assess Blood-Brain Barrier Disruption: Technical Considerations.
Hoffmann A, et al. Transl Stroke Res. 2011 Mar;2011 Mar. PMID: 21423333.

Related Fluorescent Dye Products
Fluo 3-AM

Streptavidin-FITC

Streptavidin is a tetrameric protein purified from Streptomyces sp. that binds very tightly to the vitamin biotin with a Kd of ~ 10-14 mol/l.

Coumarin 6

Coumarin 6 is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro.

Calcein

Calcein is a fluorescent dye and self-quenching probe, used as a complexometric indicator for titration of calcium ions with EDTA, and for fluorometric determination of calcium.

4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene

4,4-Difluoro-1,3,5,7,8-Pentamethyl-4-Bora-3a,4a-Diaza-s-Indacene (BODIPY 493/503) is a lipophilic fluorescent probe that localizes to polar lipids and can be used to label cellular neutral lipid contents, particularly those localized to lipid droplets, in live and fixed cells.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: FITC-Dextran supplier, Fluorescent Dye, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.