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Eosin Y Disodium

Cat. No. M20501
Eosin Y Disodium Structure
Synonym:

AMI-5

Size Price Availability Quantity
50mg USD 50  USD50 In stock
100mg USD 75  USD75 In stock
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Quality Control & Documentation
Biological Activity

Eosin Y is a form of eosin. It is most commonly used as an acidic red stain for highlighting cytoplasm material in samples.

Chemical Information
Molecular Weight 691.85
Formula C20H6Br4Na2O5
CAS Number 17372-87-1
Solubility (25°C) Water 100 mg/mL
Storage 2-8°C, protect from light, sealed
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Manuel Rueda-Fernndez, et al. Clin Exp Dermatol. Effect of the most common wound antiseptics on human skin fibroblasts

[2] Cuong Minh Quoc Le, et al. Macromol Rapid Commun. Semi-Crystalline Poly(thioether) Prepared by Visible-Light-Induced Organocatalyzed Thiol-ene Polymerization in Emulsion

[3] Lin Chen, et al. ACS Appl Mater Interfaces. Freeform Three-Dimensionally Printed Microchannels via Surface-Initiated Photopolymerization Combined with Sacrificial Molding

[4] Tapas Adak, et al. Org Lett. Metal-Free, Visible-Light-Enabled Direct C3-H Arylation of Anthranils

[5] Syed Najmul Hejaz Azmi, et al. Luminescence. Utility of eosin Y as a complexing reagent for the determination of citalopram hydrobromide in commercial dosage forms by fluorescence spectrophotometry

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