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EHNA hydrochloride is a selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 μM). EHNA hydrochloride also a potent inhibitor of adenosine deaminase. EHNA hydrochloride suppresses spontaneous differentiation of human ESCs in feeder-free conditions. EHNA hydrochloride also prevents directed neuronal differentiation.
| Molecular Weight | 313.83 |
| Formula | C14H23N5O.HCl |
| CAS Number | 58337-38-5 |
| Solubility (25°C) | Water 70 mg/mL DMSO 50 mg/mL |
| Storage | -20°C, dry, sealed |
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