Free shipping on all orders over $ 500

Eckol

Cat. No. M19461
Eckol Structure
Size Price Availability Quantity
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >95%
  • COA
  • MSDS
Biological Activity

Eckol

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight
Formula C22H20O6
CAS Number 88798-74-7
Purity >95%
Solubility
Storage at -20°C
References

[1] Sang In Lee, et al. Int J Mol Sci. Eckol Alleviates Intestinal Dysfunction during Suckling-to-Weaning Transition via Modulation of PDX1 and HBEGF

[2] Eui Jeong Han, et al. Nutrients. Eckol from Ecklonia cava Suppresses Immunoglobulin E-mediated Mast Cell Activation and Passive Cutaneous Anaphylaxis in Mice

[3] Su-Hyeon Cho, et al. Int Immunopharmacol. Eckol from Ecklonia cava ameliorates TNF-α/IFN-γ-induced inflammatory responses via regulating MAPKs and NF-κB signaling pathway in HaCaT cells

[4] Mengya Zhang, et al. Exp Ther Med. Eckol inhibits Reg3A-induced proliferation of human SW1990 pancreatic cancer cells

[5] Pradeep Paudel, et al. Mar Drugs. Eckol as a Potential Therapeutic against Neurodegenerative Diseases Targeting Dopamine D₃/D₄ Receptors

Related Others Products
Pronase E (Activity ≥ 7000 U/g)

Pronase E (Activity ≥ 7000 U/g) is a proteolytic enzyme mixture obtained from Streptomyces griseus that is able to digest proteins into individual amino acids.

D-(+)-Malic acid

D-(+)-Malic acid (D-Malic acid) is an active isomer of Malic acid and acted as a competitive inhibitor of L(-)malic acid transport.

DNJ

DNJ

GL3

GL3

Nerol

Nerol

  Catalog
Abmole Inhibitor Catalog




Keywords: Eckol supplier, Others, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.