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DiO perchlorate

Cat. No. M5121
DiO perchlorate Structure
Synonym:

DiOC18(3)

Size Price Availability Quantity
10mg USD 60 In stock
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Quality Control
  • Current batch:
  • Purity >98%
  • COA
  • MSDS
Biological Activity

DiO is used to label muscle membranes, and the membranes accessible to the dye were observed by confocal laser scanning microscopy. 3,3′-Dioctadecyloxacarbocyanine perchlorate is a cationic oxacarbocyanine dye. The absorption and fluorescence spectra of 3,3'-dioctadecyloxacarbocyanine, a cationic oxacarbocyanine dye have been studied in aqueous and nonaqueous media containing egg phosphatidylcholine (PC) as well as in different solvents of diverse nature. The maximum excitation wavelength is 484nm, and the maximum emission wavelength is 501nm.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Chemical Information
Molecular Weight 881.72
Formula C53H85ClN2O6
CAS Number 34215-57-1
Purity >98%
Solubility DMF 5 mg/mL
Storage 4°C, dry, protect from light, sealed
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  Catalog
Abmole Inhibitor Catalog 2017




Keywords: DiO perchlorate, DiOC18(3) supplier, Fluorescent Dye, inhibitors

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