Free shipping on all orders over $ 500

D-Ribose 5-phosphate disodium

Cat. No. M10450
D-Ribose 5-phosphate disodium Structure
Size Price Availability Quantity
10mg USD 99  USD110 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control
  • Current batch:
  • Purity >85%
  • COA
  • MSDS
Biological Activity

D-Ribose 5-phosphate disodium is an intermediate of the oxidative branch of the pentose phosphate pathway (PPP) and an end product of the nonoxidative branch of the PPP. D-Ribose 5-phosphate disodium is used in the synthesis of nucleotides and nucleic acids.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

Chemical Information
Molecular Weight 274.07
Formula C5H12NaO8P
CAS Number 18265-46-8
Purity >85%
Solubility Water 50 mg/mL
Storage -20°C, dry, sealed
References

Ribose-5-phosphate biosynthesis in Methanocaldococcus jannaschii occurs in the absence of a pentose-phosphate pathway
Laura L Grochowski, et al. J Bacteriol. 2005 Nov;187(21):7382-9. PMID: 16237021.

Related Products
Bombesin

Bombesin is a tetradecapeptide, which plays an important role in the release of gastrin and the activation of G-protein receptors.

Acevaltrate

Acevaltrate inhibits the Na+/K+-ATPase activity in the rat kidney and brain hemispheres with IC50s of 22.8 μM and 42.3 μM, respectively.

Valepotriate (Valtrate)

Valepotriate has anti-epileptic and anti-cancer activities, it isolated from Valeriana jatamansi Jones.

TNP-470

TNP-470 (AGM-1470; NSC 642492) is a synthetic analog of fumagillin (or Fumagillol) and a methionine aminopeptidase-2 inhibitor.

17α-Estradiol

17 alpha-Estradiol is a 5α-reductase inhibitor, and it inhibits testosterone metabolism catalyzed by 5 alpha-reductase.

  Catalog
Abmole Inhibitor Catalog 2017




Keywords: D-Ribose 5-phosphate disodium supplier, inhibitors

Contact Us

Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2020 AbMole BioScience. All Rights Reserved.