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D-(+)-Maltose monohydrate

Cat. No. M18228
D-(+)-Maltose monohydrate Structure
Size Price Availability Quantity
10g USD 25  USD25 In stock
25g USD 50  USD50 In stock
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Biological Activity

D-(+)-Maltose monohydrate

Chemical Information
Molecular Weight 360.31
Formula C12H24O12
CAS Number 6363-53-7
Form Solid
Solubility (25°C) Water 90 mg/mL
Storage 4°C, protect from light
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] D G Rathod, et al. Carbohydr Res. Dielectric relaxation and molecular interactions study of saccharides in aqueous solutions

[2] S Savolainen, et al. Vet Anim Sci. Acceptability of flavoured pharmaceutically non-active mini-tablets in pet cats tested with a rapid 3-portal acceptance test with and without food

[3] Riikka Mki, et al. Eur J Pharm Biopharm. Controlled release of saccharides from matrix tablets

[4] Katharina M Picker. Drug Dev Ind Pharm. The 3D model: explaining densification and deformation mechanisms by using 3D parameter plots

[5] T Taga, et al. Carbohydr Res. The crystal and molecular structure of the trisaccharide erlose as the monohydrate

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