Coixol is a natural product extracted from Coix Lachryma-Jobi var. ma-yuen. Coixol inhibited the expression of MUC5AC mucin gene and production of MUC5AC mucin protein, induced by EGF or TNF-α from NCI-H292 cells. Coixol decreased PMA-induced MUC5AC mucin secretion from NCI-H292 cells.
| Molecular Weight | 165.15 |
| Formula | C8H7NO3 |
| CAS Number | 532-91-2 |
| Solubility (25°C) | DMSO ≥ 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Plant growth regulators Products |
|---|
| Cybenzoxasulfyl
Cybenzoxasulfyl is an analog of Oxazosulfyl, which is also a racemate insecticide.Oxazosulfyl is a new type of benzoxazole insecticide containing an ethylsulfonylpyridine structure with a broad insecticidal spectrum. |
| Sulfiflumin
Sulfiflumin is a novel compound with insecticidal activity. |
| Thioanisole
Thioanisole is used as a raw material for the synthesis of antibiotics and insecticides. |
| Potassium carbonate
Potassium carbonate is a common potassium salt as well as a common potassium fertilizer. |
| Ethyl chloroacetate
Ethyl chloroacetate is used as a raw material for the preparation of the insecticide azoxystrobin and the herbicide ethyl chlormequat, as well as for the synthesis of 5-fluorouracil (5-FU). |
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2023 AbMole BioScience. All Rights Reserved.
