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CGP 60474

Cat. No. M6589

All AbMole products are for research use only, cannot be used for human consumption.

CGP 60474 Structure
Size Price Availability Quantity
1mg USD 40  USD40 In stock
5mg USD 90  USD90 In stock
10mg USD 130  USD130 In stock
50mg USD 400  USD400 In stock
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Quality Control & Documentation
Biological Activity

CGP60474 is a highly effective anti-endotoxin compound, it is an effective cyclin-dependent kinase (CDK) inhibitor (IC50 of CDK1/B, CDK2/E, CDK2/ A, CDK4/D, CDK5/ P25, CDK7/H and CDK9/T are 26, 3, 4, 216, 10, 200 and 13 nM, respectively). CGP60474 is a selective and ATP-competitive PKC inhibitor.

Chemical Information
Molecular Weight 355.82
Formula C18H18ClN5O
CAS Number 164658-13-3
Form Solid
Solubility (25°C) DMSO ≥ 40 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Vassilev, et al. Science. In vivo activation of the p53 pathway by small-molecule antagonists of MDM2.

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  Catalog
Abmole Inhibitor Catalog




Keywords: CGP 60474 supplier, CDK, inhibitors, activators

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