Calcein AM is one of the most popular fluorescent probes used for labeling and monitoring cellular functions of live cells. Non-fluorescent Calcein Red AM can easily get into live cells and hydrolyzes to generate strongly fluorescent Calcein Red dye. Calcein Red dye can be monitored with the common TRITC/Cy3 filter set.
|Body Surface Area (m2)||0.007||0.025||0.15||0.05||0.02||0.5|
|Animal A (mg/kg) = Animal B (mg/kg) multiplied by||Animal B Km|
|Animal A Km|
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
|Storage||-20°C, protect from light, dry, sealed|
|Related Fluorescent Dye Products|
Rose Bengal is a red or rose color dye and is anionic in nature. It is a 4,5,6,7-tetrachloro 2′,4′,5′,7′-tetraiodo derivative of fluorescein. It is widely used to detect damage to the ocular surface epithelium in ocular surface diseases such as dry eye and herpetic keratitis. Rose Bengal has mild antiviral potency. Rose Bengal is used to stain dead and degenerating cells and mucus.
Fluo-8 AM is a calcium fluorescent probe that can be loaded into protoplasts to detect calcium in apple flesh cells. The maximum excitation/emission wavelength is 495nm/516nm, which needs to be stored under -15℃ under light protection.
Z-Gly-Gly-Arg-AMC acetate is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).
Thioflavine S is a fluorescent histochemical marker of dense core senile plaques.
Thiazole orange is an unsymmetrical cyanine dye which can be conjugated to oligonucleotides (ONs) to create fluorogenic hybridisation probes. Thiazole orange can be used for reticulocyte analysis.
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