α-Glucosidase-IN-27 is an α-glucosidase inhibitor (IC50=25.78 μM).
| Molecular Weight | 436.48 |
| Formula | C22H20N4O4S |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Species | Mouse | Rat | Rabbit | Guinea pig | Hamster | Dog |
| Weight (kg) | 0.02 | 0.15 | 1.8 | 0.4 | 0.08 | 10 |
| Body Surface Area (m2) | 0.007 | 0.025 | 0.15 | 0.05 | 0.02 | 0.5 |
| Km factor | 3 | 6 | 12 | 8 | 5 | 20 |
| Animal A (mg/kg) = Animal B (mg/kg) multiplied by | Animal B Km |
| Animal A Km |
For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.
| Related Glucosidase Products |
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| Demethylisoencecalin
α-Glucosidase-IN-35 is a kind of chromene. |
| 3-Hydroxybakuchiol
3-Hydroxybakuchiol is an electron transport chain (ETC) inhibitor. 3-Hydroxybakuchiol has antitumor activity, and induces tumor cell apoptosis. |
| Gcase activator 2
Gcase activator 2 activator (EC50=3.8 μM). |
| α-Glucosidase-IN-26
α-Glucosidase-IN-26 is an α-glucosidase inhibitor (IC50=4.63 µM). |
| Mortatarin F
Mortatarin F is an inhibitor of α‑glucosidase with an IC50 of 8.7 μM. |
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