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3X FLAG peptide

Cat. No. M14802
3X FLAG peptide Structure
Size Price Availability Quantity
5mg USD 130  USD130 In stock
10mg USD 220  USD220 In stock
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Quality Control & Documentation
Biological Activity

3X FLAG Peptide is a synthetic peptide with a 3-time repeated DYKXXD motif.

Chemical Information
Molecular Weight 2861.87
CAS Number 402750-12-3
Solubility (25°C) Water 2 mg/mL (ultrasonic and adjust pH to 3 with HCl)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Conversion of different model animals based on BSA (PMID: 27057123)
Species Mouse Rat Rabbit Guinea pig Hamster Dog
Weight (kg) 0.02 0.15 1.8 0.4 0.08 10
Body Surface Area (m2) 0.007 0.025 0.15 0.05 0.02 0.5
Km factor 3 6 12 8 5 20
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of Compound A used for a mouse (20 mg/kg) to a dose based on the BSA for a rat, multiply 20 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for Compound A of 10 mg/kg.

References

[1] Minna M Koskela, et al. Purification of Protein-complexes from the Cyanobacterium Synechocystis sp. PCC 6803 Using FLAG-affinity Chromatography

[2] Adam C Rupper, et al. Induction of guanylate binding protein 5 by gamma interferon increases susceptibility to Salmonella enterica serovar Typhimurium-induced pyroptosis in RAW 264.7 cells

[3] Greta J Wegner, et al. Real-time surface plasmon resonance imaging measurements for the multiplexed determination of protein adsorption/desorption kinetics and surface enzymatic reactions on peptide microarrays

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Keywords: 3X FLAG peptide supplier, Peptides, inhibitors, activators


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