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2-Thiouracil is an established antithyroid pyrimidine analog and an extensively investigated agent for the early detection and targeting of metastatic melanotic melanoma. 2-thiouracil is effectively incorporated into the RNA and leads to alterations in the structure of the proteins synthesized. In addition, 2-Thiouracil is also a selective inhibitor of neuronal nitric oxide synthase antagonising tetrahydrobiopterin-dependent enzyme activation and dimerization.
| Molecular Weight | 128.15 |
| Formula | C4H4N2OS |
| CAS Number | 141-90-2 |
| Form | Solid |
| Solubility (25°C) | DMSO 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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