| Cat.No. | Name | Information |
|---|---|---|
| M54606 | Desirudin | Desirudin is a thrombin inhibitor that inhibits thrombosis and venous stasis thrombosis.Desirudin can be used in studies related to thrombocytopenia or platelet dysfunction. |
| M52508 | TP508 | TP508 is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule. |
| M52507 | Succinyl-(Pro58, D-Glu65)-Hirudin (56-65) (sulfated) | Succinyl-(Pro58,D-Glu65)-Hirudin (56-65) (sulfated) is a hirugen-like peptide, and has high affnity for thrombin than Hirugen, with a KD < 100 nM. |
| M52506 | Thrombin receptor peptide ligand | Thrombin receptor peptide ligand is a thrombin receptor antagonist peptide that can be used as an antithrombotic agent. |
| M52505 | Z-Gly-Pro-Arg-4MβNA | Z-Gly-Pro-Arg-4MβNA is the cleavage of the substrate of thrombin to release free 4-methoxy-2-naphthylamine (4MβNA). |
| M52504 | Sar-Pro-Arg-pNA | Sar-Pro-Arg-pNA is a chromogenic substrate of α-thrombin. |
| M52503 | Hirullin P18 | Hirullin P18 is a potent thrombin inhibitor. |
| M49429 | Lepirudin | Lepirudin is a recombinant hirudin and also a potent irreversible thrombin inhibitor with anticoagulant activity in heparin-induced thrombocytopenia (HIT). |
| M43947 | Enoxaparine | Enoxaparine is a low molecular heparin that binds to antithrombin (AT) and accelerates its inhibition of factor Xa.Enoxaparine has a higher affinity for factor Xa than for thrombin, and its action on thrombin does not require HCII (heparin cofactor II). |
| M42616 | TFLLRNPNDK-NH2 | TFLLRNPNDK-NH2 is a biological active peptide. |
| M30468 | Avatrombopag maleate | Avatrombopag maleate (AKR-501) is an orally active, nonpeptide thrombopoietin (TPO) receptor agonist (EC50=3.3 nM). Avatrombopag maleate mimics the biological activities of TPO. Avatrombopag maleate increases platelet production by activating the intracellular signaling system, and promotes production of platelets and megakaryocytes from hemopoietic precursor cells. Avatrombopag maleate is a substrate of cytochrome P450 (CYP) 2C9 and CYP3A. |
| M30263 | NP-313 | NP-313 is a potent antithrombotic agent that inhibits platelet aggregation and activation. NP-313 has dual inhibition of thromboxane A 2 synthesis and selective inhibition of SOCC-mediated Ca2+ inward flow. |
| M28647 | Napsagatran hydrate | Napsagatran hydrate is a novel and specific thrombin inhibitor. |
| M28072 | Rafutrombopag diolamine | Rafutrombopag diolamine is the derivative of Rafutrombopag. Rafutrombopag is a thrombopoietin receptor agonist. |
| M27676 | TPO agonist 1 | TPO agonist 1 is a thrombopoietin (TPO) agonist. It would be useful as promoters of thrombopoiesis and megakaryocytopoiesis to treat thrombocytopenia. |
| M24959 | Befovacimab | Befovacimab (BAY 1093884) is a fully human monoclonal IgG2 antibody able to bind to tissue factor pathway inhibitor (TFPI). Befovacimab can be used for haemophilia A/B research. |
| M22471 | Rafutrombopag | Rafutrombopag is a thrombopoietin (TPO) agonist. |
| M21312 | BAY 1217224 | BAY 1217224 is a neutral non-premedication inhibitor of Thrombin with good oral pharmacokinetics. |
| M20396 | Argatroban | Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant. |
| M14539 | Dabigatran ethyl ester hydrochloride | Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor. |
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