Catalog

STING Stimulator of Interferon Genes

Inhibitors

Cat.No.	Name	Information
M10459	MSA-2	MSA-2 is an orally available non-nucleotide STING agonist with antitumor activity. MSA-2 shows EC50 values of 8.3 and 24 μM for human STING isoforms WT and HAQ, respectively.
M10299	c-di-AMP	c-di-AMP (Cyclic diadenylate) is a STING agonist, it binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway.
M10126	H-151	H-151 is a highly potent, selective and covalent antagonist of STING, reduces TBK1 phosphorylation and suppresses human STING palmitoylation.
M10125	C-178	C-178 is a covalent inhibitor of STING, binds to Cys91 on STING to block its palmitoylation.
M9923	SR-717	SR-717 is a non-nucleotide STING agonist with EC50s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively.
M9893	C-176	C-176 is a potent small-molecule inhibitor of STING.
M9729	diABZI STING agonist 1 (compound 3)	diABZI STING agonist-1 (compound 3) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.
M9084	STING-Inducer-1	STING-Inducer-1 (ML RR-S2 CDA) is an inducer of STING (stimulator of interferon genes).
M1999	Vadimezan (DMXAA)	Vadimezan (DMXAA; ASA-404) acts as a tumor vascular disrupting agent (tumor-VDA), is also a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines.