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ROCK Rho-associated protein kinase

Cat.No.  Name Information
M1817 Y-27632 dihydrochloride Y-27632 is a potent, selective inhibitor of Rho-associated protein kinases (ROCK) with IC50 values of 140-220 nM for ROCK1 and ROCK2. In addition, Y-27632 inhibited LPA-induced entosis.
M5168 GSK269962A GSK269962A is a potent ROCK inhibitor with IC50 values of 1.6 and 4 nM for recombinant human ROCK1 and ROCK2, respectively.
M7388 TC-S 7001 TC-S 7001 is a potent and highly selective ROCK inhibitor; orally active.
M4938 H-1152 H-1152, an isoquinolinesulfonamide derivative, is a more specific, stronger and membrane-permeable inhibitor of Rho-kinase with a Ki value of 1.6 nM, but poor inhibitor of other serine/threonine kinases.
M49531 Glycyl H-1152 hydrochloride Glycyl H-1152 hydrochloride is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride.
M49530 Chroman 1 dihydrochloride Chroman 1 dihydrochloride is a highly potent and selective ROCK inhibitor.
M49529 CCG-232964 CCG-232964 is an orally active inhibitor of Rho/MRTF/SRF.
M49527 AR-13324 analog mesylate AR-13324 analog mesylate is an analog of AR-13324.
M49526 CAY10746 CAY10746 is a selective Rho kinase (ROCK) inhibitor.
M49525 3-(4-Pyridyl)indole 3-(4-Pyridyl)indole (Rockout) is a Rho-kinase (ROCK) inhibitor, with an IC50 of 25 μM.
M41597 ROCK-IN-9 ROCK-IN-9 is a ROCK inhibitor.
M41596 ROCK-IN-7 ROCK-IN-7 is a ROCK kinase inhibitor.
M41595 ROCK-IN-8 ROCK-IN-8 is a ROCK inhibitor, with an IC50 value less than 100 nM.
M41594 CaMKP inhibitor sodium CaMKP inhibitor sodium is a selective inhibitor of ROCK1 with an IC50 value of 14 nM.
M41593 Rho-Kinase-IN-3 Rho-Kinase-IN-3 is a potent and selective Rho kinase (ROCK1) inhibitor with an IC50 value of 8 nM.
M41592 THK01 THK01 is a potent ROCK2 inhibitor with IC50 values of 5.7 and 923 nM for ROCK2 and ROCK1, respectively.
M41591 ROCK2-IN-6 ROCK2-IN-6 is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research.
M41590 ROCK2-IN-6 hydrochloride ROCK2-IN-6 hydrochloride is a selective ROCK2 inhibitor, can be used for ROCK mediated diseases, autoimmune diseases and inflammation research.
M40627 BA-1076 BA-1076 is a ROCK1/2 inhibitor that can be used in glaucoma-related studies.
M40626 AR-13503 AR-13503 is an active metabolite of Netarsudil and a PKC/ROCK inhibitor that inhibits angiogenesis and enhances retinal pigment epithelium (RPE) permeability. It can be used in studies related to diabetic macular edema and macular degeneration.
M40625 Zelasudil Zelasudil (RXC-007) is a selective ROCK2 inhibitor for studies related to idiopathic pulmonary fibrosis.
M40624 OPL-0401 OPL-0401 is an orally active small molecule Rho-kinase (ROCK 1/2) inhibitor for studies related to non-proliferative diabetic retinopathy.
M40623 Fasudil mesylate Fasudil mesylate is a potent inhibitor of ROCKs with neuroprotective activity for studies related to cerebral infarction.
M31008 Sovesudil hydrochloride Sovesudil (PHP-201) hydrochloride is a potent, ATP-competitive, locally acting Rho kinase (ROCK) inhibitor with IC50s of 3.7 and 2.3 nM for ROCK-I and ROCK-II, respectively. Sovesudil hydrochloride lowers intraocular pressure (IOP) without inducing hyperemia.




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