|M10423||DT2216||DT2216 is a selective B-cell lymphoma extra large (BCL-XL) proteolysis-targeting chimera (PROTAC).|
|M10386||MT-802||MT-802 is a potent BTK degrader based on PROTAC technology, it induces Bruton's tyrosine kinase (BTK) knockdown.|
|M10385||PROTAC KRASG12C Degrader-LC-2||PROTAC KRASG12C Degrader-LC-2 is a potent first-in-class PROTAC capable of degrading endogenous KRAS G12C, with DC50s between 0.25 and 0.76 μM.|
|M10384||Homo-PROTAC pVHL30 degrader 1||Homo-PROTAC pVHL30 degrader 1 is a pVHL30 degrader based on PROTAC and a potent VHL inhibitor.|
|M10383||Homo-PROTAC cereblon degrader 1 (OUN20985)||Homo-PROTAC cereblon degrader 1 (OUN20985) is a potent and efficient cereblon (CRBN) degrader with minimal effects on IKZF1 and IKZF3.|
|M10382||PROTAC SGK3 degrader-1||PROTAC SGK3 degrader-1 (SGK3-PROTAC1) is a potent SGK3 degrader, it is a PROTAC conjugate of the 308-R SGK inhibitor with the VH032 VHL binding ligand, targeting SGK3.|
|M10381||TD-165||TD-165 is a PROTAC-based cereblon (CRBN) degrader.|
|M10380||dBET57||dBET57 is a novel BRD4 heterobifunctional small-molecule ligand (PROTAC) which exhibits significant and selective degradation of BRD4 BD1 but is inactive on BRD4 BD2.|
|M10379||BSJ-03-123||BSJ-03-123 is a novel, potent CDK6-selective small-molecule degrader (PROTAC).|
|M10067||Ac4GalNAz||Ac4GalNAz is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.|
|M9838||VH032-PEG6-C4-Cl||(S,R,S)-AHPC-PEG6-C4-Cl is a small molecule HaloPROTAC that incorporates the (S,R,S)-AHPC based VHL ligand and 6-unit PEG linker.|
|M9824||MZ 1||MZ 1 is a PROTAC BRD4 degrader, with Kd values of 382/120, 119/115, and 307/228 nM for BRD4 BD1/2, BRD3 BD1/2, and BRD2 BD1/2, respectively.|
|M9791||5-Ethynyl-2'-deoxyuridine||5-Ethynyl-2'-deoxyuridine is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.|
|M9396||A1874||A1874 is a BRD4-degrading PROTAC which inhibits many cancer cell lines proliferation, with DC50 of 32 nM (induce BRD4 degradation in cells).|
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