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Abmole Inhibitor Catalog 2017

PDK1 3'-phosphoinositide-dependent kinase 1


Cat.No.  Name Information
M9360 Dicoumarol Dicoumarol is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50s of 0.37 and 19.42 μM, respectively.
M7562 BX517 BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM.
M4832 NVP-BAG956 NVP-BAG956 is a potent, ATP-competitive and selective dual PDK1 and class I PI 3-K inhibitor (IC50 values are 245, 56, 446, 35 and 117 nM for PDK1 and PI 3-K p110 -α, -β, -δ, and -γ respectively).
M3731 HS-173 HS-173 is a potent PI3Kα inhibitor with IC50 of 0.8 nM.
M2311 BX-912 BX912 is a selective potent PDK1 inhibitor with IC50 of 12 nM.
M2310 BX-795 BX795 is a potent and specific TBK1, IKKε and PDK-1 inhibitor with IC50 of 6 nM, 41 nM and 111 nM, respectively.
M2115 GSK2334470 GSK2334470 is a highly specific and potent inhibitor of PDK1 with IC50 of 10 nM.
M1848 OSU-03012 OSU-03012 is a novel and potent inhibitor of PDK-1 with an IC50 of 5 µM.

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