| Cat.No. | Name | Information |
|---|---|---|
| M8538 | ML354 | ML354 is a potent and selective PAR4 (protease activated receptor-4) antagonist. |
| M50156 | DT-9045 | DT-9045 is a protease-activated receptor 2 (PAR-2) antagonist that can be used in tumor-related studies. |
| M49643 | I-287 | I-287 is a orally active selective PAR2 inhibitor that acting as a negative allosteric regulator on Gαq and Gα12/13 activity and their downstream effectors. |
| M41918 | FLLRN | FLLRN is a biological active peptide. |
| M41917 | YFLLRNP | YFLLRNP is a biological active peptide. |
| M41916 | TFLLRN-NH2 | TFLLRN-NH2 is a biological active peptide. |
| M41915 | SFNGGP-NH2 | SFNGGP-NH2 is a biological active peptide. |
| M41914 | Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 | Ala-parafluoroPhe-Arg-Cha-Cit-Tyr-NH2 is a biological active peptide. |
| M41913 | Q94 hydrochloride | Q94 hydrochloride, a selective PAR1 antagonist (IC50=916 nM), can selectively block PAR1/Gαq interaction and signalling. |
| M31039 | 2-Furoyl-LIGRLO-amide TFA | 2-Furoyl-LIGRLO-amide TFA is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0.. |
| M31038 | GB-110 hydrochloride | GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 hydrochloride selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. |
| M30574 | Atopaxar | Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar, an antiplatelet agent, interferes with platelet signaling. Atopaxar can be used for the research of atherothrombotic disease. |
| M30544 | 2-Furoyl-LIGRLO-amide | 2-Furoyl-LIGRLO-amide is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0.. |
| M30134 | Atopaxar hydrobromide | Atopaxar (E5555) hydrobromide is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar hydrobromide, an antiplatelet agent, interferes with platelet signaling. Atopaxar hydrobromide can be used for the research of atherothrombotic disease. |
| M29230 | AZ8838 | AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2. |
| M28812 | I-191 | I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist. |
| M28523 | UDM-001651 | UDM-001651 is a potent, selective, and orally bioavailable protease-activated receptor 4 (PAR4) antagonist (IC50=4 nM; Kd=1.4 nM). UDM-001651 shows antiplatelet potency (IC50=25 nM) in a γ-thrombin-induced platelet-rich plasma aggregation assay (γ-Thr PRP). |
| M28045 | GB83 | GB83 is a potent PAR2 antagonist. GB83 reverses neutrophil elastase‐induced synovitis and pain. GB83 blocks the effect of MET-1 supernatant on NG neurons. |
| M28044 | GB-110 | GB-110 is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist. GB-110 selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. |
| M27954 | CBK289001 | CBK289001 is a tartrate-resistant acid phosphatase (TRAP/ACP5) inhibitor. CBK289001 inhibits TRAP 5bMV, TRAP 5bOX and TRAP 5aOX with IC50s of 125 µM, 4.21 µM and 14.2 µM, respectively. |
| M21101 | BMS-986120 | BMS-986120 is a first-in-class oral protease-activated receptor 4 (PAR4) inhibitor with IC50 values of 9.5 nM in human and 2.1 nM in monkey blood.BMS-986120 exhibits potent and selective antiplatelet effects. BMS-986120 has potent and selective antiplatelet effects and can be used in studies related to arterial thrombosis. |
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