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Abmole Inhibitor Catalog 2017

Integrin Integrin


Cat.No.  Name Information
M10557 RGD peptide TFA RGD peptide TFA acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation.
M10480 Tetraiodothyroacetic acid (tetrac) Tetraiodothyroacetic acid (tetrac) is a thyrointegrin receptor antagonist. Tetraiodothyroacetic acid blocks the actions of T4 and 3,5,3'-triiodo-L-thyronine (T3) at the cell surface receptor for thyroid hormone on integrin αvβ3.
M10211 Obtustatin Obtustatin is a potent integrin α1β1 inhibitor with IC50 of 0.8 nM for α1β1 binding to type IV collagen.
M10209 Cyclo(-RGDfK) Cyclo (-RGDfK) is an effective and specific αvβ3 integrin inhibitor.
M9781 E7820 E7820 is a α2 integrin inhibitor which suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells.
M9173 Cilengitide trifluoroacetate Cilengitide is a potent integrin inhibitor for αvβ3 and αvβ5 receptor with IC50 of 4.1 nM, 79 nM in cell-free assays respectively.
M8975 CWHM-12 CWHM-12 is a potent inhibitor of αV integrins with IC50 values of 0.2, 0.8, 1.5, and 1.8 nM for αvβ8, αvβ3, αvβ6, and αvβ1, respectively.
M8939 Firategrast Firategrast (SB-683699) is an orally bioavailable alpha4 beta1/alpha4 beta7 integrin antagonist.
M6905 Leukadherin 1 Leukadherin 1 is a allosteric activator of CD11b/CD18.
M6018 Tirofiban hydrochloride monohydrate Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist
M5852 Lifitegrast Lifitegrast is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.
M5241 GLPG0187 GLPG0187 inhibited the progression of bone metastasis. Maximum efficacy of inhibition of bone metastasis was achieved when GLPG0187 was combined with the standard-of-care metastatic breast cancer treatments.
M3789 ATN-161 TFA ATN-161 TFA salt is a novel small peptide inhibitor of integrin α5β1; a beta integrin antagonist with antitumor activity.
M2976 RGD RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and bind to integrins.
M2042 Cilengitide Cilengitide (EMD 121974, NSC 707544) is a selective inhibitor of αvβ3 integrin and αvβ5 integrin with IC50 of 1 nM and 140 nM, respectively.
M1618 Vedolizumab Vedolizumab is a monoclonal antibody binds to integrin α4β7.

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