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GPCR19/TGR5 GPCR19/TGR5

Inhibitors

Cat.No.	Name	Information
M11152	Deoxycholic acid sodium salt	Deoxycholic acid sodium salt activates the G protein-coupled bile acid receptor TGR5.
M9727	SBI-115	SBI-115 is a TGR5 (GPCR19) antagonist, it decreases hepatic cystogenesis with polycystic liver diseases via inhibiting TGR5.
M7398	TC-SP 14	TC-SP 14 is a potent S1P₁ receptor agonist.
M2588	TGR5 Receptor Agonist	TGR5 Receptor Agonist is a potent TGR5(GPCR19) agonist which showed improved potency in the U2-OS cell assay (pEC50 = 6.8) and in melanophore cells (pEC50 = 7.5).