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Inhibitors
| Cat.No. | Name | Information |
|---|---|---|
| M8879 | AOA hemihydrochloride | Aminooxyacetic acid hemihydrochloride is a malate-aspartate shuttle (MAS) inhibitor which also inhibits the GABA degradating enzyme GABA-T. |
| M6010 | Tiagabine HCl | Tiagabine Hydrochloride is the hydrochloride salt form of tiagabine, a nipecotic acid derivative with anticonvulsant property. A selective gamma-aminobutyric acid (GABA) reuptake inhibitor. |
| M6009 | Tiagabine | Tiagabine is an anti-convulsive medication and a selective gamma-aminobutyric acid (GABA) reuptake inhibitor. |
| M5870 | Pentylenetetrazol | Pentylenetetrazol displays activity as a central nervous system and respiratory stimulant. It is considered a non-competitive GABA(A) receptor antagonist. |
| M5730 | L-Cycloserine | L-cycloserine irreversibly inhibit GABA pyridoxal 5′-phosphate-dependent aminitransferase in E. coli, as well in the brains of various animals in a time-dependent manner, results in increased levels of gamma-aminobutyric acid (GABA), which is an inhibitory neurotransmitter in vivo. |
| M5669 | Gabapentin HCl | Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain. |
| M5653 | Flumazenil | Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses. |
| M5575 | Dihydroergotoxine mesylate | Dihydroergotoxine mesylate is a complex of closely related alkaloid salts; Binds with high affinity to the GABAA receptor Cl- channel, producing an allosteric interaction with the benzodiazepine site. |
| M5442 | Baclofen | Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant. |
| M5390 | Afloqualone | Afloqualone is a agonist of GABA receptor . |
| M5378 | Acamprosate calcium | Acamprosate calcium (Campral EC) is a GABA receptor agonist and glutamate system modulator. |
| M3981 | Bilobalide | Bilobalide, a natural product extracted from Ginkgo biloba leaf, is known to exhibit a number of pharmacological activities. |
| M3968 | Dihydromyricetin | Dihydromyricetin is a natural antioxidant flavonoid from Ampelopsis grossedentata. |
| M3600 | Gabapentin | Gabapentin is a pharmaceutical agent, specifically a GABA analogue. |
| M3344 | Nefiracetam | Nefiracetam is a GABAergic, cholinergic, and monoaminergic neuronal systems enhancer for Ro 5-4864-induced convulsions. |
| M2555 | AWD 131-138 | AWD 131-138 is a new low-affinity partial benzodiazepine receptor agonist with potent anticonvulsant and anxiolytic properties in rodent models. |
| M2347 | (+)-Bicuculline | (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. |
| M2005 | (R)-Baclofen | (R)-baclofen is a selective gamma-aminobutyric acid(B) agonist. |
| M1893 | Etomidate | Etomidate (marketed as Amidate) is a general anesthetic with GABA modulatory and GABA-mimetic actions. |
| M1891 | SKF 89976A hydrochloride | SKF 89976A hydrochloride is a potent GABA uptake inhibitor, selective for GAT-1. |
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