|M9341||AZD-7648||AZD-7648 is a potent and selective DNA-PK inhibitor.|
|M6284||Compound 401||Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 μM) that also targets mTOR but not PI3K in vitro.|
|M6205||YU238259||YU238259 is a novel inhibitor of homology-dependent DNA repair(HDR), but does not inhibit non-homologous end-joining (NHEJ), in cell-based GFP reporter assays.|
|M6077||LTURM34||LTURM34 is a specific DNA-PK inhibitor, 170-fold more selective for DNA-PK activity compared to PI3K activity, with IC50 value of 0.034 μM.|
|M2798||KU-0060648||KU-0060648 is a dual inhibitor of DNA-PK and PI3Kα, PI3Kβ, PI3Kδ with IC50 of 8.6 nM and 4 nM, 0.5 nM, 0.1 nM respectively, less inhibition of PI3Kγ with IC50 of 0.59 μM.|
|M2308||NU7026||NU7026 is a DNA-PK inhibitor with IC50 of 0.23 μM.|
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