Inhibitors
Cat.No. | Name | Information |
---|---|---|
M9909 | Eltanexor | Eltanexor, also known as KPT-8602, is a second-generation exportin-1 (CRM1) inhibitor with IC50 values of 20−211 nM in 10 AML lines. |
M6230 | Verdinexor | Verdinexor (KPT-335) is an orally bioavailable, selective XPO1/CRM1 inhibitor. |
M3152 | KPT-330 | KPT-330 is a first-in-class, oral, selective inhibitor of Nuclear Export (SINE) compound, works by binding to and inhibiting the nuclear export protein XPO1 (also known as CRM1). |
M2795 | KPT-276 | KPT-276 is an orally bioavailable selective CRM1 inhibitor. |
M2794 | KPT-185 | KPT-185 is a selective CRM1 inhibitor. |
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