Cat.No. | Name | Information |
---|---|---|
M1637 | ABT-263 | ABT-263 (Navitoclax) is a potent, orally bioavailable inhibitor of the antiapoptotic Bcl-2 family members Bcl-2, Bcl-x (L), and Bcl-w. |
M2017 | ABT-199 (Venetoclax) | ABT-199 is a highly potent, orally bioavailable and BCL-2 inhibitor. ABT-199 is the first inhibitor targeting Bcl-2 and PPI. |
M5273 | S63845 | S63845 is a potent and selective myeloid cell leukemia 1 (MCL1) inhibitor; binds human MCL1 with a Kd of 0.19 nM. |
M13528 | AZD-5991 | AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay. |
M13526 | A-1155463 | A-1155463 is a highly potent and selective BCL-XL inhibitor with an EC50 of 70 nM in Molt-4 cell. |
M54126 | Bim BH3, Peptide IV | Bim BH3, Peptide IV is a 26-residue peptide from BH3-only protein Bim, which belongs to the pro-apoptotic group of the Bcl-2 family of proteins. |
M53413 | Bax inhibitor peptide, negative control | Bax inhibitor peptide, negative control is a inhibitor of Bax. |
M53412 | Bad BH3 (mouse) | Bad BH3 (mouse) is a biological active peptide. |
M53411 | Bid BH3 (80-99) | Bid BH3 (80-99) is a biological active peptide. |
M53410 | Bak BH3 | Bak BH3 is derived from the BH3 domain of Bak, can antagonize the function of Bcl-xL in cells. |
M53409 | F1324 | F1324 is a potent, high affinity peptidic inhibitor of B cell lymphoma 6 (BCL6) with an IC50 of 1 nM. |
M45260 | Pelcitoclax | Pelcitoclax is a potent Bcl-2/Bcl-xl inhibitor with anti-tumor and pro-apoptotic activities. |
M45060 | ABBV-467 | ABBV-467 is a type IV selective MCL-1 inhibitor for studies related to multiple myeloma. |
M45050 | Sonrotoclax | Sonrotoclax is an orally active, potent Bcl2 inhibitor.Sonrotoclax exhibits potent cell killing effects on a variety of lymphoma and leukemia cell lines. Sonrotoclax is effective in killing a variety of lymphoma and leukemia cell lines and may be used in studies related to hematologic tumors. |
M41328 | WK499 | BCL6-IN-10 is a BCL6 inhibitor. |
M41327 | Hrk BH3 | Hrk BH3 is a biological active peptide. |
M41326 | Bik BH3 | Bik BH3 is a biological active peptide. |
M41325 | Bim BH3 | Bim BH3 is a biological active peptide. |
M41324 | Bcl-B inhibitor 1 | Bcl-B inhibitor 1 is a Bcl-B inhibitor. |
M41323 | r8 Bid BH3 | r8 Bid BH3 is a biological active peptide. |
M41322 | Mcl-1 inhibitor 15 | Mcl-1 inhibitor 15 is a Mcl-1 inhibitor (Ki: 0.02 nM). |
M41321 | Lacutoclax | Lacutoclax is a Bcl-2 inhibitor with antineoplastic activity. |
M41320 | Mcl-1 inhibitor 13 | Mcl-1 inhibitor 13 is a MCL-1 inhibitor (Ki: 8.2 nM). |
M41319 | Mcl-1 inhibitor 12 | Mcl-1 inhibitor 12 is a MCL-1 inhibitor (Ki: 0.22 nM). |
M41318 | Mcl-1 inhibitor 16 | Mcl-1 inhibitor 16 is a mitochondrial targeting Platinum-based inhibitor of Mcl-1. |
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