Certificate of Analysis

 

Product Name: Zoledronic acid monohydrate
Catalog Number: M5032
CAS Number: 165800-06-6

Physical and Chemical Properties
Formula: C5H12N2O8P2
Molecular Weight: 290.1
Solubility: water:7 mg/ml
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: Zoledronic acid monohydrate Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: Zoledronic acid monohydrate(CGP 42446; ZOL 446) is an activator of protein kinase C with apoptotic effects on multiple myeloma cell lines. It inhibited proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 uM.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.