Certificate of Analysis


Catalog Number: M5032
Product Name: Zoledronic acid monohydrate
CAS Number: 165800-06-6

Physical and Chemical Properties
Formula: C5H12N2O8P2
Molecular Weight: 290.1
Solubility: water´╝Ü7 mg/ml
Storage: at -20°C
Chemical Structure: Zoledronic acid monohydrate Structure
Analytical Data
HPLC: Shows Min >98% purity
H-NMR: Consistent with structure
Product Information
Description: Zoledronic acid monohydrate(CGP 42446; ZOL 446) is an activator of protein kinase C with apoptotic effects on multiple myeloma cell lines. It inhibited proliferation of human foetal osteoblastic cell line (hFOB) with an IC50 of 40 uM.
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.