Certificate of Analysis
| Product Name: | Zetomipzomib maleate |
| Catalog Number: | M21515 |
| CAS Number: | 2170983-62-5 |
Physical and Chemical Properties
| Formula: | C34H46N4O12 |
| Molecular Weight: | 702.75 |
| Solubility: | DMSO ≥ 200 mg/mL |
| Storage: | 2-8℃, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ＞99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Zetomipzomib (KZR-616) maleate is a first-in-class inhibitor of immunoproteasome that selectively targets the immunoproteasome subunit LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50:131/179 nM=hLMP7/mLMP7). Potential of Zetomipzomib maleate for use in multiple autoimmune diseases. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |