Certificate of Analysis
| Product Name: | YQ128 |
| Catalog Number: | M10687 |
| CAS Number: | 2454246-18-3 |
Physical and Chemical Properties
| Formula: | C27H29ClN2O4S2 |
| Molecular Weight: | 545.11 |
| Form: | Solid |
| Solubility: | DMSO ≥ 100 mg/mL |
| Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | YQ128 is a potent, selective second-generation NLRP3 inflammatory body inhibitor,IC50 0.30 μM. YQ128 significantly and selectively inhibits the production of IL-1β, but does not inhibit the production of TNF-α. YQ128 can cross the blood-brain barrier to reach the central nervous system. YQ128 has anti-inflammatory activity. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |