Certificate of Analysis


Product Name: WYE-354
Catalog Number: M1755
CAS Number: 1062169-56-5

Physical and Chemical Properties
Formula: C24H29N7O5
Molecular Weight: 495.5
Solubility: DMSO 90 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: WYE-354 Structure
Analytical Data
QC Standard: 98.0%
H-NMR: Consistent with structure
Product Information
Description: WYE-354 is a cell-permeable pyrazolopyrimidine compound that acts as a potent and ATP-competitive mTOR inhibitor (IC50 = 5 nM with S6K as the substrate and 100 µM ATP).
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.