Certificate of Analysis

 

Product Name: Trofinetide acetate
Catalog Number: M21112
CAS Number: 853400-76-7 (free base)

Physical and Chemical Properties
Formula: C15H25N3O8
Molecular Weight: 375.36
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Analytical Data
QC Standard: >99%
H-NMR: Consistent with structure
Product Information
Description: Trofinetide (NNZ-2566) acetate is a novel analogue of the amino-terminal tripeptide of IGF-1, stimulates synaptic maturation, inhibits the production of inflammatory cytokines and the hyperactivation of microglia and astrocytes, and increases the amount of available IGF-1 that can bind to the IGF-1 receptor. Sequence: G-α-Me-Pro-E.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.