Certificate of Analysis
| Product Name: | Trilaciclib hydrochloride |
| Catalog Number: | M11419 |
| CAS Number: | 1977495-97-8 |
Physical and Chemical Properties
| Formula: | C24H32Cl2N8O |
| Molecular Weight: | 519.46988 |
| Solubility: | Water ≥ 20 mg/mL |
| Storage: | 4°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | >99% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | Trilaciclib hydrochloride is a potent, first-in-class reversible inhibitor of CDK4/6, inhibiting CDK4/cyclin D1 and CDK6/cyclin D3 with IC50 values of 1 nM and 4 nM, respectively. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |