Product Name: | Tenofovir alafenamide hemifumarate |
Catalog Number: | M20783 |
CAS Number: | 1392275-56-7 |
Formula: | C46H62N12O14P2 |
Molecular Weight: | 1069 |
Solubility: | DMSO 100 mg/mL, Water 50 mg/mL |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: | ![]() |
HPLC: | Shows Min >99% purity |
H-NMR: | Consistent with structure |
Description: | Tenofovir alafenamide (TAF, GS-7340) hemifumarate is a prodrug of tenofovir but results in significantly higher intracellular tenofovir concentrations and lower serum levels. Tenofovir alafenamide is a novel nucleotide reverse transcriptase inhibitor for the treatment of HIV-1 infection. |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |