Certificate of Analysis

 

Product Name: TASIN-1 hydrochloride
Catalog Number: M8757
CAS Number: 1678515-13-3

Physical and Chemical Properties
Formula: C18H28N2O3S · HCl
Molecular Weight: 388.95
Solubility: Water: 2 mg/mL
Storage: Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
Chemical Structure: TASIN-1 hydrochloride Structure
Analytical Data
QC Standard: >98%
H-NMR: Consistent with structure
Product Information
Description: TASIN-1 (Truncated APC Selective INhibitor-1) targets EBP- (Emopamil-binding protein; D8-D7 sterol isomerase) dependent cholesterol biosynthesis and selectively induces cellular cholesterol depletion and apoptotic death in human colorectal cancer (CRC) cultures harboring APC truncations under lipid-deficient conditions (0.
   
Stability and Solubility Advice: Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide.
We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details.