Certificate of Analysis
| Product Name: | TAME hydrochloride |
| Catalog Number: | M28857 |
| CAS Number: | 1784-03-8 |
Physical and Chemical Properties
| Formula: | C14H23ClN4O4S |
| Molecular Weight: | 378.87 |
| Form: | Solid |
| Solubility: | DMSO 155 mg/mL (ultrasonic); Water ≥ 100 mg/mL |
| Storage: | -20°C, dry, sealed |
| Chemical Structure: |  |
Analytical Data
| QC Standard: | ≥99.0% |
| H-NMR: | Consistent with structure |
Product Information
| Description: | TAME hydrochloride is an inhibitor of anaphase-promoting complex/cyclosome (APC/C or APC), which binds to APC/C and prevents its activation by Cdc20 and Cdh1, produces mitotic arrest. TAME hydrochloride is not cell permeable. |
| Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |