Product Name: | TAK-659 hydrochloride |
Catalog Number: | M10688 |
CAS Number: | 1952251-28-3 |
Formula: | C17H22ClFN6O |
Molecular Weight: | 380.85 |
Solubility: | DMSO < 1 mg/mL |
Storage: |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
Chemical Structure: | ![]() |
QC Standard: | >99.0% |
H-NMR: | Consistent with structure |
Description: | TAK-659 hydrochloride is a highly selective, reversible, orally potent dual inhibitor of SYK/FLT3 that acts on SYK and FLT3 IC50 The values are 3.2 nM and 4.6 nM, respectively. TAK-659 hydrochloride induces tumor cell death without acting on non-tumor cells, with potential to study chronic lymphocytic leukemia (CLL). |
Stability and Solubility Advice: | Information concerning product stability, particularly in solution, has rarely been reported and in most cases we can only offer a general guide. We recommend that stock solutions, once prepared, are stored aliquoted in tightly sealed vials and used within 1 month. Avoid repeated freeze and thaw cycles. Storage conditions for some special products should refer to their storage details. |